What are the side effects of Semaglutide?

Most common: nausea, decreased appetite, mild GI discomfort during titration. These diminish as your body adapts. Slow titration starting at 0.25 mg minimizes effects.

Semaglutide vs Tirzepatide — which one for me?

Semaglutide is the established GLP-1-only option with longer real-world data. Tirzepatide adds GIP-receptor activity for stronger results (20-22% vs 15-17%).

Dr. Kenika explaining semaglutide mechanism and dose plan at TRT Bangkok

Weight-Loss · GLP-1 Single-Pathway

Semaglutide Thailand

Authentic Semaglutide from Novo Nordisk — Wegovy for chronic weight management, Ozempic for Type 2 diabetes. Cold-chain delivery across Thailand. International patients travel to our Pattaya clinic; Singapore monthly courier.

US FDA-approved · Ozempic 2017 · Wegovy 2021 · Novo Nordisk
14.9% average body-weight reduction (STEP-1, 68 weeks)
Established GLP-1 with longest real-world safety data

Request consultation → Get Started ↓

Dr. Kenika consulting on Semaglutide GLP-1 therapy at TRT Bangkok

Dr. Kenika, Medical Director

Medical Council of Thailand · Personal supervision

Authentic

Novo Nordisk Pen

Doctor-Led

Dr. Kenika · MD

Trusted

Verified 5.0

Cold-Chain

Pharmacy-Grade Delivery

Body-weight reduction · STEP-1 trial

−14.9%

Mean body-weight reduction in the STEP-1 trial at 68 weeks on semaglutide 2.4 mg — the active molecule in Wegovy and Ozempic.

Wilding et al., NEJM 2021 · n=1,961 non-diabetic adults

What that means for you

Your weight

That's −12.7 kg — you'd weigh 72.3 kg.

Based on the 14.9% trial-mean. Individual outcomes vary.

Dr. Kenika explaining personalized GLP-1 weight-loss treatment plan on tablet during consultation at TRT Bangkok

Dr. Kenika explaining GLP-1 mechanism to patient

Semaglutide consultation room at TRT Bangkok

Semaglutide molecule consultation at TRT Bangkok

Licensed medical facility · Real photos · Dr. Kenika

The Science

What is Semaglutide?

Semaglutide is a GLP-1 receptor agonist — a synthetic analog of the natural gut-hormone GLP-1. Once-weekly subcutaneous injection. Manufactured by Novo Nordisk. In STEP-1^[1], adults on Wegovy 2.4 mg lost 14.9% body weight over 68 weeks.

Appetite Regulation

GLP-1 activates receptors in the hypothalamus, reducing hunger and increasing satiety.

Glucose Control

GLP-1 stimulates insulin and suppresses glucagon — the diabetes mechanism that won Ozempic FDA approval.

Gastric Slowing

Slows stomach emptying — food stays longer, prolonging fullness. Also the source of nausea during titration.

For dual-pathway alternatives see Tirzepatide. For triple-pathway research option see Retatrutide.

Manufacturer-Direct

Two Brands · One Molecule · One Manufacturer

Wegovy

Novo Nordisk

FDA-approved June 2021 for chronic weight management. Dose range 0.25-2.4 mg weekly.

Read about Wegovy →

Ozempic

Novo Nordisk

FDA-approved December 2017 for Type 2 diabetes. Dose range 0.25-2 mg weekly. Significant weight loss documented as secondary effect.

Read about Ozempic →

Program Investment

Authentic Semaglutide Program

Doctor-led · Authentic Novo Nordisk · Wegovy / Ozempic

from 1,990 ฿ per shot

↑ Take-home pens available from 14,990 ฿/month

Every program includes

Doctor consultation

Individualized dose plan

Ongoing monitoring

Cold-chain delivery

Semaglutide is dispensed as Wegovy (chronic weight management) or Ozempic (Type 2 diabetes) — both authentic Novo Nordisk products. Same molecule, indication-specific labels.

Discuss your Semaglutide program on WhatsApp →

See full take-home pen options (14,990 ฿ — 29,990 ฿)

0.25 mg pen

14,990 ฿

Initiation · weeks 1-4

0.50 mg pen

14,990 ฿

Titration · weeks 5-8

1.0 mg pen

16,990 ฿

Therapeutic · weeks 9-12

1.7 mg pen

23,590 ฿

Up-titration · weeks 13-16

2.4 mg pen

29,990 ฿

Maximum · weeks 17+

Per-shot pricing at higher doses confirmed during your consultation. Final program pricing depends on your dose plan and treatment duration. Thai pharmacy advertising regulations preclude binding online prices — your exact figure is shared in private medical review.

Comparison

Semaglutide vs Tirzepatide vs Retatrutide

View full comparison table

Dimension	Semaglutide	Tirzepatide	Retatrutide
Average weight loss	14.9% (STEP-1, Wegovy 2.4 mg)	20.9% (SURMOUNT-1)	24%+ (Phase 2)
Receptor pathways	GLP-1	GLP-1 + GIP	GLP-1 + GIP + Glucagon
FDA status	Approved · Wegovy 2021, Ozempic 2017	Approved · Mounjaro 2022, Zepbound 2023	Phase 3 complete
Real-world safety data	Longest (since 2017)	Strong (since 2022)	Limited (research-stage)
Common brand(s)	Wegovy, Ozempic (Novo Nordisk)	Mounjaro, Zepbound (Eli Lilly)	No commercial brand yet
Best fit for	First-time GLP-1, established safety	Stronger results than GLP-1 alone	Highest BMI, prior GLP-1 plateau

Dr. Kenika reviews your medical history during the private consultation to recommend the right choice.

Your Personalized Trajectory

See your expected trajectory on Semaglutide.

Trajectory based on the STEP-1 clinical-trial mean. Your individualized program is confirmed in consultation — this is an evidence-based estimate, not a guarantee.

Current weight

Goal weight

Treatment

Semaglutide

Your trajectory · based on STEP-1 mean (Semaglutide)

Weeks to goal

—

Projected loss

—

Monthly investment

from 1,990 ฿/shot

Book your personalized program review →

Estimator uses peer-reviewed clinical-trial mean data. Individual outcomes vary based on adherence, baseline BMI, comorbidities, and lifestyle factors. Final program plan determined in private medical consultation.^[ref]

Titration Protocol

Standard Semaglutide Dose-Escalation

Wegovy follows a 5-step titration over 16-20 weeks. Each step lasts 4 weeks. Ozempic uses a similar schedule capped at 2 mg.

View Wegovy 5-step titration

Weeks 1-4

0.25 mg weekly

Adaptation phase. GI system acclimates.

Weeks 5-8

0.5 mg weekly

First therapeutic step. Some early weight loss possible.

Weeks 9-12

1 mg weekly

Up-titration if tolerated. Common Ozempic maintenance.

Weeks 13-16

1.7 mg weekly

Intermediate Wegovy dose.

Weeks 17+

2.4 mg weekly

Wegovy maximum — STEP-1 efficacy reference^[1].

Source: Novo Nordisk Wegovy & Ozempic prescribing information.

How It Works

A simple, medically supervised path to your Semaglutide program.

Discovery Call

15-minute WhatsApp with our clinic team. Share your goals, history, and questions. No commitment.

Medical Evaluation

Dr. Kenika reviews your history. Labs ordered if needed. Treatment plan decided based on your specific clinical picture.

Start Treatment

First dose at clinic or cold-chain delivery to your address. Titration plan + side-effect support from day one.

Track & Adjust

Weekly check-ins during titration. Dose adjusted to your response. Sustainable maintenance plan together.

Book your free discovery call →

Why TRT Bangkok

Three foundations of our weight-loss program.

DOCTOR-LED CARE

Every Semaglutide patient is personally supervised by Dr. Kenika — medical history review, HbA1c monitoring where relevant, dose decisions, titration adjustments. No intake-form-only approval.

100%

MANUFACTURER-DIRECT

Authentic Semaglutide from Novo Nordisk via cold-chain pharmacy distribution. Batch numbers and expiry dates intact. No compounded substitutes, no grey-market sourcing.

Novo Nordisk

THREE ACCESS MODES

In-clinic in Pattaya, concierge nurse to your hotel in Bangkok, or online consultation with cold-chain delivery in Phuket and beyond.

3 Ways

Your Doctor

Meet Your Medical Director

Dr. Kenika Norrachetdecha, MD

Medical Director · TRT Bangkok

Hormone MedicineBrain HealthMetabolic OptimisationWeight Loss

Dr. Kenika Norrachetdecha, MD, leads TRT Bangkok's clinical practice. She specialises in hormone optimisation, regenerative medicine, and metabolic health, with advanced training under Dr. Mark Gordon (USA). Every Semaglutide patient — Wegovy or Ozempic — is personally supervised by Dr. Kenika across all access points.

3.000+

Patients Treated

500+

IV Treatments

3.000+

TRT Treatments

1.000+

GLP-1 Treatments

International Training

Advanced neuroregenerative medicine training under Dr. Mark Gordon (USA) — featured on The Joe Rogan Experience.

Dr. Kenika Norrachetdecha with Dr. Mark Gordon at HEAT Conference

With Dr. Mark Gordon (USA)

HEAT Conference — Neuroregenerative Medicine Training

Thai Medical License #72509 · Council Member #71253 — Verify ↗

Frequently Asked

Common Questions About Semaglutide

Is this authentic Wegovy or Ozempic?

Yes. Both Wegovy and Ozempic are manufactured by Novo Nordisk A/S. Each pen ships through cold-chain pharmaceutical distribution with batch numbers and expiry dates intact.

Wegovy vs Ozempic — what is the difference?

Same active molecule (Semaglutide). Ozempic is FDA-approved for Type 2 diabetes (2017) at 0.25-2 mg/week^[3]. Wegovy is FDA-approved for chronic weight management (2021) at 0.25-2.4 mg/week^[2].

How much weight will I lose?

In STEP-1^[1], adults on Wegovy 2.4 mg weekly lost an average 14.9% of body weight over 68 weeks. Real-world Thailand patients typically see 12-17% over 6-12 months.

What are the side effects?

Most common: nausea, decreased appetite, mild GI discomfort during titration. These typically diminish over weeks. Slow titration starting at 0.25 mg significantly reduces effects.

Semaglutide vs Tirzepatide — which one?

Semaglutide is the established GLP-1-only option with longest real-world data. Tirzepatide adds GIP-receptor activity for stronger results. See Tirzepatide Thailand.

How do I store Semaglutide?

Refrigerator 2-8°C. Once in use, room temperature (below 30°C) for up to 56 days. Do not freeze. Never leave pen on car dashboards in Thai climate.

What if I miss a dose?

Within 5 days: inject as soon as possible, then resume normal weekly schedule. After 5 days: skip and take next dose on the regular day.

Patient Reviews

What patients say

5.0 / 5

15 verified Google Reviews

Real reviews from real patients on Google Business Profile. Currently 5.0 ★ from 15 verified reviews — and growing.

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Read all reviews on Google Business Profile →

Ready to start Semaglutide?

Request a consultation. Our clinic team responds within minutes on WhatsApp.

Request consultation

Medically reviewed by Dr. Kenika, Medical Director

Member, Medical Council of Thailand · Endocrinology & Metabolic Medicine

This page is reviewed for medical accuracy. Content is informational and does not substitute for individualized medical advice.

Sources

Peer-reviewed primary sources, FDA prescribing information, manufacturer documentation.

View all 5 sources

Wilding JPH, Batterham RL, Calanna S, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP-1). N Engl J Med. 2021;384(11):989-1002. doi:10.1056/NEJMoa2032183. View on NEJM ↗
U.S. FDA. Wegovy (semaglutide) injection prescribing information. Initial Approval: 2021. FDA label (PDF) ↗
U.S. FDA. Ozempic (semaglutide) injection prescribing information. Initial Approval: 2017. FDA label (PDF) ↗
Marso SP, Bain SC, Consoli A, et al. Semaglutide and Cardiovascular Outcomes (SUSTAIN-6). N Engl J Med. 2016;375(19):1834-1844. View on NEJM ↗
American Diabetes Association. Pharmacologic Approaches to Glycemic Treatment — Standards of Care 2024. Diabetes Care. 2024;47(Suppl 1):S158-S178. View ↗